4-Iodo-1-methyl-1H-imidazole → HCID 121409535, compound

HRID 2019636Notes

Reaction equation

HRID 2019636 reaction equation
[CH3:1][n:2]1[cH:6][c:5](I)[n:4][cH:3]1.[CH3:7][C:8]([O:11][C:12]([N:14]1[CH2:28][CH2:27][CH:17]([CH2:18][O:19][c:20]2[c:25]([NH2:26])[n:24][cH:23][c:22](B3OC(C)(C)C(C)(C)O3)[cH:21]2)[CH2:16][CH2:15]1)=[O:13])([CH3:10])[CH3:9]>>[CH3:1][n:2]1[cH:6][c:5]([c:22]2[cH:21][c:20]([O:19][CH2:18][CH:17]3[CH2:27][CH2:28][N:14]([C:12]([O:11][C:8]([CH3:10])([CH3:9])[CH3:7])=[O:13])[CH2:15][CH2:16]3)[c:25]([NH2:26])[n:24][cH:23]2)[n:4][cH:3]1

Participants

8

Reactant 2

HCID 27734634-Iodo-1-methyl-1H-imidazoleHCID 131748360HCID 131748360, compound

Product 1

HCID 121409535HCID 121409535, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 25953Cesium fluorideReagentHCID 178454893HCID 178454893, compoundCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-d453cfde27014dfdb9423caadbde0d8b
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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