Hydrochloric Acid → N-(1-benzylpiperid-4-yl)-2-hydroxy-4-amino-5-nitrobenzamide

HRID 202025Notes

Reaction equation

HRID 202025 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([c:16]2[c:17]([OH:29])[cH:18][c:19]([NH:25][C:26](=[O:27])[CH3:28])[c:20]([N+:22](=[O:23])[O-:24])[cH:21]2)=[O:30])[CH2:12][CH2:13]1.[CH3:33][CH2:34][OH:35].[ClH:36].[Na+:32].[OH-:31].[OH2:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([c:16]2[c:17]([OH:29])[cH:18][c:19]([NH2:25])[c:20]([N+:22](=[O:23])[O-:24])[cH:21]2)=[O:30])[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 12821333N-(1-benzylpiperid-4-yl)-2-hydroxy-4-acetamido-5-nitrobenzamide

Product 1

HCID 12821334N-(1-benzylpiperid-4-yl)-2-hydroxy-4-amino-5-nitrobenzamide

Sources & evidence

ORD record
ord-adc08df96bfe47ada400176e5c285352
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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