Hydrochloric Acid → N2-(4-(Oxazol-5-yl)phenyl)-N4-((tetrahydro-2H-pyran-4-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

HRID 202047Notes

Reaction equation

HRID 202047 reaction equation
[CH3:39][OH:40].[ClH:38].[o:1]1[cH:2][n:3][cH:4][c:5]1-[c:6]1[cH:7][cH:8][c:9]([NH:12][c:13]2[n:14][c:15]([NH:30][CH2:31][CH:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[c:16]3[c:17]([n:18]2)[CH2:19][CH2:20][N:21]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:22]3)[cH:10][cH:11]1>>[o:1]1[cH:2][n:3][cH:4][c:5]1-[c:6]1[cH:7][cH:8][c:9]([NH:12][c:13]2[n:14][c:15]([NH:30][CH2:31][CH:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[c:16]3[c:17]([n:18]2)[CH2:19][CH2:20][NH:21][CH2:22]3)[cH:10][cH:11]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59333789tert-Butyl 2-(4-(oxazol-5-yl)phenylamino)-4-((tetrahydro-2H-pyran-4-yl)methylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Product 1

HCID 59333782N2-(4-(Oxazol-5-yl)phenyl)-N4-((tetrahydro-2H-pyran-4-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-5978f3f29c4f4715b1fe2d8cf964733f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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