Acetic Acid → 8-(1-Hydroxy-cyclopropanecarbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[B-:1]([F:2])([F:3])([F:4])[F:5].[C:23]([OH:24])(=[O:25])[CH3:26].[F:27][C:28]([O:29][c:30]1[cH:31][cH:32][c:33]([N:36]2[C:37](=[O:46])[C:38]3([CH2:39][CH2:40]2)[CH2:41][CH2:42][NH:43][CH2:44][CH2:45]3)[cH:34][cH:35]1)([F:47])[F:48].[OH:49][C:50]1([C:53](=[O:54])[OH:55])[CH2:51][CH2:52]1.[n:6]1([O:7][C:8]([N:9]([CH3:10])[CH3:11])=[N+:12]([CH3:13])[CH3:14])[c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[n:21][n:22]1>>[F:27][C:28]([O:29][c:30]1[cH:31][cH:32][c:33]([N:36]2[C:37](=[O:46])[C:38]3([CH2:39][CH2:40]2)[CH2:41][CH2:42][N:43]([C:53]([C:50]2([OH:49])[CH2:51][CH2:52]2)=[O:54])[CH2:44][CH2:45]3)[cH:34][cH:35]1)([F:47])[F:48]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-386fb5b587e14e89b2f98b53a776d3d7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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