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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 202057Generated: October 29, 2026

Acetic Acid → 8-(1-Hydroxy-cyclopropanecarbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/202057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantTetrafluoroborateHCID 26255—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant1-Hydroxy-1-cyclopropanecarboxylic acidHCID 2733160—
Reactant2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 66742759—
Product8-(1-Hydroxy-cyclopropanecarbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577931—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-386fb5b587e14e89b2f98b53a776d3d7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)