N,N-Dimethylethylenediamine → 5-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-N-[2-(dimethylamino)ethyl]-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide

HRID 202193Notes

Reaction equation

HRID 202193 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][c:16]([C:32](=[O:33])[O:34][CH2:35][CH3:36])[c:17](=[O:31])[n:18](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[c:19]2[CH3:20])[cH:7][cH:8]1.[CH3:37][N:38]([CH2:39][CH2:40][NH2:41])[CH3:42]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][c:16]([C:32](=[O:33])[NH:41][CH2:40][CH2:39][N:38]([CH3:37])[CH3:42])[c:17](=[O:31])[n:18](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[c:19]2[CH3:20])[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 58218050Ethyl 5-[2-(4-cyanophenyl)-2H-pyrazole-3-yl]-6-methyl-2-oxo-1-(3-trifluoromethylphenyl)-1,2-dihydropyridine-3-carboxylate

Product 1

HCID 670929825-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-N-[2-(dimethylamino)ethyl]-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide

Sources & evidence

ORD record
ord-20365208735b4877a903f2fbe6215f18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…