Methanol → 4-(1-Benzenesulfonylpiperidin-4-ylmethyl)-phenylamine

HRID 202367Notes

Reaction equation

HRID 202367 reaction equation
[CH3:32][OH:33].[F:1][C:2]([F:3])([F:4])[C:28]([NH:5][c:6]1[cH:7][cH:8][c:9]([CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:17][CH2:18]2)[cH:10][cH:11]1)=[O:29].[Li+:30].[OH-:31].[OH2:34]>>[NH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:17][CH2:18]2)[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961HydroxideHCID 962WaterHCID 28486Lithium ionHCID 218770242,2,2-trifluoro-N-(4-(1-benzenesulfonyl-piperidin-4-ylmethyl)-phenyl]acetamide

Product 1

HCID 218770334-(1-Benzenesulfonylpiperidin-4-ylmethyl)-phenylamine

Sources & evidence

ORD record
ord-0f0ef586076747e4bdc28bb4ba7353d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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