Ethylene → 8-chloro-5-methyl-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[CH3:1][c:2]1[cH:8][c:7]([C:9]([NH:11]OC([C:12](C)(C)[CH3:13])=O)=[O:10])[c:5]([Cl:6])[cH:4][cH:3]1.C=C>>[CH3:1][c:2]1[c:8]([c:7]2[c:5]([Cl:6])[cH:4][cH:3]1)[CH2:13][CH2:12][NH:11][C:9]2=[O:10]Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-352306d77ce54aa0a45f658cfe5b13fd
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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