Ethylene → 8-chloro-5-methyl-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[CH2:1]=[CH2:2].[CH3:3][c:4]1[cH:10][c:9]([C:11]([NH:13]OC(C(C)(C)C)=O)=[O:12])[c:7]([Cl:8])[cH:6][cH:5]1>>[CH3:3][c:4]1[c:10]([c:9]2[c:7]([Cl:8])[cH:6][cH:5]1)[CH2:2][CH2:1][NH:13][C:11]2=[O:12]Participants
6
Reactant 2
Product 1
Reagents, catalysts & solvents 3
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-88761d767fac4b80bc12f035474447d8
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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