Hydrochloric Acid → 4'-Amino-2'-methyl-biphenyl-3-carboxylic acid (4-morpholin-4-yl-phenyl)-amide

HRID 202612Notes

Reaction equation

HRID 202612 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][c:10]([CH3:35])[c:11](-[c:14]2[cH:15][c:16]([C:20]([NH:21][c:22]3[cH:23][cH:24][c:25]([N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[cH:26][cH:27]3)=[O:34])[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:36].[CH3:38][OH:39].[ClH:37]>>[NH2:7][c:8]1[cH:9][c:10]([CH3:35])[c:11](-[c:14]2[cH:15][c:16]([C:20]([NH:21][c:22]3[cH:23][cH:24][c:25]([N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[cH:26][cH:27]3)=[O:34])[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59822359[2-Methyl-3'-(4-morpholin-4-yl-phenylcarbamoyl)-biphenyl-4-yl]-carbamic acid tert-butyl ester

Product 1

HCID 598223324'-Amino-2'-methyl-biphenyl-3-carboxylic acid (4-morpholin-4-yl-phenyl)-amide

Sources & evidence

ORD record
ord-be597434185143c2877d0305ac5bdb9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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