Ethyl Acetate → tert-Butyl {1-[4-(aminocarbonyl)-6-cyanopyridin-2-yl]piperidin-4-yl}carbamate
Reaction equation
[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[Cu:25]([C:26]#[N:27])[C:28]#[N:29].[Fe+2:78].[NH2:1][C:2](=[O:3])[c:4]1[cH:5][c:6]([N:11]2[CH2:12][CH2:13][CH:14]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:15][CH2:16]2)[n:7][c:8]([Cl:10])[cH:9]1.[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1.[cH:42]1[cH:43][cH:44][c:45]([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c-:53]2[cH:54][cH:55][cH:56][cH:57]2)[cH:58][cH:59]1.[cH:60]1[cH:61][cH:62][c:63]([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c-:71]2[cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77]1>>[NH2:1][C:2](=[O:3])[c:4]1[cH:5][c:6]([N:11]2[CH2:12][CH2:13][CH:14]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:15][CH2:16]2)[n:7][c:8]([C:26]#[N:27])[cH:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-42589d9efc594213ba9ebc24916febc6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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