Methanol → 3-(4-Chloro-benzylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[BH4-:23].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH2:13])[CH2:11][CH2:12]1.[CH3:25][OH:26].[Cl:14][c:15]1[cH:16][cH:17][c:18]([CH:19]=[O:20])[cH:21][cH:22]1.[Na+:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][CH2:19][c:18]2[cH:17][cH:16][c:15]([Cl:14])[cH:22][cH:21]2)[CH2:11][CH2:12]1Participants
6
Sources & evidence
- ORD record
- ord-1878546b53d5449bb252b83ebd86c65e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…