Ammonia → (3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol

HRID 2029075Notes

Reaction equation

HRID 2029075 reaction equation
[CH3:1][S:2]([N:5]1[CH2:11][C@H:9]([OH:10])[C:8](=O)[CH2:7][CH2:6]1)(=[O:4])=[O:3].[NH3:12].[K+].CC(C([BH-](C(C(C)C)C)C(C(C)C)C)C)C>>[CH3:1][S:2]([N:5]1[CH2:11][C@H:9]([OH:10])[C@H:8]([NH2:12])[CH2:7][CH2:6]1)(=[O:4])=[O:3]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 23676661Potassium hydridotris(3-methylbutan-2-yl)borate(1-)HCID 178504951HCID 178504951, compound

Product 1

HCID 178017013(3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol

Reagents, catalysts & solvents 1

HCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-ebd4f80a3bc54ab5961aad073158d409
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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