Ammonia → (3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol

HRID 2029135Notes

Reaction equation

HRID 2029135 reaction equation
COB([C@@H]1[C@@H](C)[C@H](C(C)(C)[C@@H]2C1)C2)[C@@H]3[C@@H](C)[C@H](C(C)(C)[C@@H]4C3)C4.[NH3:1].[CH3:2][S:3]([N:6]1[CH2:12][C@H:10]([OH:11])[C:9](=O)[CH2:8][CH2:7]1)(=[O:5])=[O:4]>>[CH3:2][S:3]([N:6]1[CH2:12][C@H:10]([OH:11])[C@H:9]([NH2:1])[CH2:8][CH2:7]1)(=[O:5])=[O:4]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 13549401(+)-B-MethoxydiisopinocampheylboraneHCID 178504951HCID 178504951, compound

Product 1

HCID 178017013(3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol

Reagents, catalysts & solvents 1

HCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-109b65faddc44b539d47138a7e9d12a6
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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