Bromide ion → Tert-butyl 4-[4-[6-amino-5-(1,3-benzoxazol-2-yl)-3-pyridyl]-3-(1-hydroxyethyl)pyrazol-1-yl]piperidine-1-carboxylate
Reaction equation
[Br-:1].[CH3:2][Mg+:3].[NH2:4][c:5]1[c:6](-[c:31]2[o:32][c:33]3[c:34]([n:35]2)[cH:36][cH:37][cH:38][cH:39]3)[cH:7][c:8](-[c:11]2[c:12]([CH:29]=[O:30])[n:13][n:14]([CH:16]3[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]3)[cH:15]2)[cH:9][n:10]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[CH3:2][CH:29]([c:12]1[c:11](-[c:8]2[cH:7][c:6](-[c:31]3[o:32][c:33]4[c:34]([n:35]3)[cH:36][cH:37][cH:38][cH:39]4)[c:5]([NH2:4])[n:10][cH:9]2)[cH:15][n:14]([CH:16]2[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]2)[n:13]1)[OH:30]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4d4acd118c254d479b0b07213d7e7f7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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