HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dibromo-4-methylpyridine → 5-Bromo-4-methylpyridine-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dibromo-4-methylpyridine | HCID 819338 | — |
| Reactant | sodium bis(trimethylsilyl)azanide | HCID 178504303 | — |
| Catalyst | [1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethane | HCID 75537289 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Bromo-4-methylpyridine-3-carbonitrile | HCID 7060681 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|---|
| Source dataset | 39k HTE dataset from Pfizer |
| ORD ID | ord-09afbe879b964925abe0a8883d3aea77 |
| Source note | 39k HTE dataset from Pfizer |