3,5-Dibromo-4-methylpyridine → 5-Bromo-4-methylpyridine-3-carbonitrile
Reaction equation
[CH3:1][c:2]1[c:8](Br)[cH:7][n:6][cH:5][c:3]1[Br:4].[CH3:9][Si]([N:10]([Si](C)(C)C)[Na])(C)C>>[CH3:1][c:2]1[c:8]([C:9]#[N:10])[cH:7][n:6][cH:5][c:3]1[Br:4]Participants
6
Reactant 2
Product 1
Reagents, catalysts & solvents 3
Conditions
- Temperature
- 120 °C
Sources & evidence
- ORD record
- ord-09afbe879b964925abe0a8883d3aea77
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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