Tetrabutylammonium Cyanide → 5-Bromo-4-methylpyridine-3-carbonitrile

HRID 2031029Notes

Reaction equation

HRID 2031029 reaction equation
CCCC[N+](CCCC)(CCCC)CCCC.[C-:1]#[N:2].[CH3:3][c:4]1[c:10](Br)[cH:9][n:8][cH:7][c:5]1[Br:6]>>[CH3:3][c:4]1[c:10]([C:1]#[N:2])[cH:9][n:8][cH:7][c:5]1[Br:6]

Participants

6

Reactant 2

HCID 165872Tetrabutylammonium CyanideHCID 8193383,5-Dibromo-4-methylpyridine

Product 1

HCID 70606815-Bromo-4-methylpyridine-3-carbonitrile

Reagents, catalysts & solvents 3

HCID 11714597Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)CatalystHCID 679Dimethyl SulfoxideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-f7bac379b541429d89887352ebe28141
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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