HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031444Generated: November 1, 2026
1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate
https://huagongshe.com/reaction/2031444
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid | HCID 268472 | — |
| Reactant | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| Reagent | Cesium carbonate | HCID 10796 | — |
| Catalyst | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Catalyst | Dichloronickel;1,2-dimethoxyethane | HCID 15773433 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate | HCID 102543294 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-09c68c7e5df348d587b9bc402d48c0f3 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
