1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate
Reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH:12]([C:13](O)=O)[CH2:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].[CH3:14][c:15]1[n:19][cH:18][cH:17]c(Br)[cH:16]1>>[CH3:14][c:15]1[n:19][cH:18][cH:17][c:13]([CH:12]2[N:8]([C:6]([O:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])[CH2:9][CH2:10][CH2:11]2)[cH:16]1Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-09c68c7e5df348d587b9bc402d48c0f3
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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