Dimethylformamide → 2-(N-BOC-N-methylamino)-5-bromopyridine

HRID 203193Notes

Reaction equation

HRID 203193 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[n:6][cH:7]1.[C:16](=[O:17])([O-:18])[O-:19].[CH3:22][I:23].[Cs+:20].[Cs+:21].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[CH3:16])[n:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6328Methyl iodideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 162178432-(Boc-amino)-5-bromopyridine

Product 1

HCID 111969422-(N-BOC-N-methylamino)-5-bromopyridine

Sources & evidence

ORD record
ord-b209d90ab8c94bdf9190f1b1bd549861
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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