Ammonia → (3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol
Reaction equation
[CH3:1][S:2]([N:5]1[CH2:11][C@H:9]([OH:10])[C:8](=O)[CH2:7][CH2:6]1)(=[O:4])=[O:3].[NH3:12].B[C@H]1[C@H](C)[C@H](C(C)(C)[C@@H]2C1)C2.B[C@H]3[C@H](C)[C@H](C(C)(C)[C@@H]4C3)C4.CN(CCN(C)C)C>>[CH3:1][S:2]([N:5]1[CH2:11][C@@H:9]([OH:10])[C@H:8]([NH2:12])[CH2:7][CH2:6]1)(=[O:4])=[O:3]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-8f5ed5d8292b4f7ebe81060ffa5da278
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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