Bicarbonate Ion → (6-Chloro-4-cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)-[4-(2,5-dichloro-phenoxy)-pyridin-3-yl]-methanone

HRID 203264Notes

Reaction equation

HRID 203264 reaction equation
[C:56](=[O:57])([OH:58])[O-:59].[CH3:42][SiH:43]([CH3:44])[N:45]([CH3:46])[Si:47]([CH3:48])([CH3:49])[CH3:50].[CH:1]1([N:4]2[CH2:5][CH2:6][N:7]([C:14](=[O:15])[c:16]3[cH:17][n:18][cH:19][cH:20][c:21]3[O:22][c:23]3[c:24]([Cl:30])[cH:25][cH:26][c:27]([Cl:29])[cH:28]3)[c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]32)[CH2:2][CH2:3]1.[Cl:31][c:32]1[cH:33][cH:34][cH:35][c:36]([C:37]([O:38][OH:39])=[O:40])[cH:41]1.[Cl:51][C:52]([O:53][CH3:54])=[O:55].[Cl:61][CH2:62][Cl:63].[Na+:60]>>[CH:1]1([N:4]2[CH2:5][CH2:6][N:7]([C:14](=[O:15])[c:16]3[cH:17][n:18][cH:19][cH:20][c:21]3[O:22][c:23]3[c:24]([Cl:30])[cH:25][cH:26][c:27]([Cl:29])[cH:28]3)[c:8]3[cH:9][cH:10][c:11]([Cl:31])[cH:12][c:13]32)[CH2:2][CH2:3]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 6586Methyl chloroformateHCID 70297m-Chloroperbenzoic acidHCID 589711N-dimethylsilyl-N-trimethylsilylmethanamineHCID 53311869(4-Cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)(4-(2,5-dichloro-phenoxy)-pyridin-3-yl)-methanone

Product 1

HCID 53311952(6-Chloro-4-cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)-[4-(2,5-dichloro-phenoxy)-pyridin-3-yl]-methanone

Sources & evidence

ORD record
ord-a59641552d8f4fe78c825778ecd0d7e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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