Tetrahydrofuran → 2-Chloro-5-(thiophene-2-carbonyl)-benzenesulfonamide

HRID 203423Notes

Reaction equation

HRID 203423 reaction equation
[CH2:6]([Li:7])[CH2:8][CH2:9][CH3:10].[Cl:11][c:12]1[c:13]([S:24]([NH2:25])(=[O:26])=[O:27])[cH:14][c:15]([C:16](=[O:17])[N:18]([O:19][CH3:20])[CH3:21])[cH:22][cH:23]1.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[cH:1]1[cH:2][cH:3][s:4][cH:5]1>>[cH:1]1[cH:2][c:3]([C:16]([c:15]2[cH:14][c:13]([S:24]([NH2:25])(=[O:26])=[O:27])[c:12]([Cl:11])[cH:23][cH:22]2)=[O:17])[s:4][cH:5]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8030ThiopheneHCID 581073994-chloro-N-methoxy-N-methyl-3-sulfamoyl-benzamideHCID 178418339Butyllithium

Product 1

HCID 581074962-Chloro-5-(thiophene-2-carbonyl)-benzenesulfonamide

Sources & evidence

ORD record
ord-c61274b61e854f408b03957e90f97b6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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