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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2035547Generated: October 30, 2026

6-[4-Methoxybenzyl-(6-morpholinopyridin-3-yl)amino]-4-[(trifluoroacetyl)amino]pyridine-3-carboxylic acid ethyl ester → HCID 67412646, compound

https://huagongshe.com/reaction/2035547

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-[4-Methoxybenzyl-(6-morpholinopyridin-3-yl)amino]-4-[(trifluoroacetyl)amino]pyridine-3-carboxylic acid ethyl esterHCID 86657943—
SolventMethanolHCID 887—
SolventWaterHCID 962—
SolventPotassium CarbonateHCID 11430—
ProductHCID 67412646HCID 67412646100%

Reaction Steps

51 mg of 6-[4-methoxybenzyl-(6-morpholinopyridin-3-yl)amino]-4-[(trifluoroacetyl)amino]pyridine-3-carboxylic acid ethyl ester was dissolved in 5 mL of methanol, to which 3 mL of 2 mol/L potassium carbonate in water was added, and stirred at room temperature for 4 hours. To the reaction mixture water was added, extracted with ethyl acetate, the extract was washed with saturated saline, and dried on anhydrous sodium sulfate. The solvent was evaporated to obtain 42 mg (yield 100%) of the title compound as a light yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575153B2
Source datasetuspto-grants-2013_11
ORD IDord-9ee59c8823ed4d239c60dcbdef661608
Source noteuspto-grants-2013_11