反应详情

51 mg of 6-[4-methoxybenzyl-(6-morpholinopyridin-3-yl)amino]-4-[(trifluoroacetyl)amino]pyridine-3-carboxylic acid ethyl ester was dissolved in 5 mL of methanol, to which 3 mL of 2 mol/L potassium carbonate in water was added, and stirred at room temperature for 4 hours. To the reaction mixture water was added, extracted with ethyl acetate, the extract was washed with saturated saline, and dried on anhydrous sodium sulfate. The solvent was evaporated to obtain 42 mg (yield 100%) of the title compound as a light yellow solid.

1. additionwas added
2. extractionextracted with ethyl acetate
3. washthe extract was washed with saturated saline
4. dry with materialdried on anhydrous sodium sulfate
5. customThe solvent was evaporated