HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 46174615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67231245 | HCID 67231245 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 46174615 | HCID 46174615 | 95% |
Reaction Steps
(R)-2-([1,2,4]triazolo[4,3-a]pyridin-3-yl)-8-(2-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylpropoxy)quinoline (0.030 g, 0.072 mmol) was added to 1 N HCl in methanol and stirred for 30 minutes, then evaporated, co-evaporated once in methanol and triturated in DCM to isolate 23 mg of 95% pure desired product as a beige solid. MS ESI (+) m/z 379 (M+1) detected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575145B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a0c23e2a0d5549e7b99de2dedbec117d |
| Source note | uspto-grants-2013_11 |