Potassium Carbonate → HCID 68557601, compound

HRID 2036073Notes

Reaction equation

HRID 2036073 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[S:12][N:11]=[C:10]([CH3:13])[N:9]=2)=[CH:6][CH:7]=1.Cl.[NH:15]1[CH2:20][CH2:19][C:18]2([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[NH:23][C:22](=[O:30])[O:21]2)[CH2:17][CH2:16]1.C(=O)([O-])[O-].[K+].[K+]>>[CH3:13][C:10]1[N:9]=[C:8]([C:5]2[N:4]=[N:3][C:2]([N:15]3[CH2:16][CH2:17][C:18]4([C:25]5[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=5[NH:23][C:22](=[O:30])[O:21]4)[CH2:19][CH2:20]3)=[CH:7][CH:6]=2)[S:12][N:11]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 109218293-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazineHCID 13050640Spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one--hydrogen chloride (1/1)

Product 1

HCID 68557601HCID 68557601, compound

Procedure

The object product (72 mg, 76%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (51 mg), spiro[3,1-benzoxazine-4,4′-piperidin]-2(1H)-one hydrochloride (89 mg) and potassium carbonate (70 mg).

Sources & evidence

ORD record
ord-dd4c610f3e8246e082bcd0abcadc6380
Source dataset
uspto-grants-2013_11
Patent number
US08575167B2

Reaction notes

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