HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 8-[6-(3-Methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | 3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one | HCID 20286475 | — |
| Product | 8-[6-(3-Methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one | HCID 68555053 | — |
Reaction Steps
The object product (72 mg, 29%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (130 mg), 3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one (142 mg) and potassium carbonate (127 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-2b4ba1ae98d14a319506ff22e20f1b5e |
| Source note | uspto-grants-2013_11 |