HCID 68557503, compound → HCID 68555950, compound

Participants

Reaction Steps

To a solution of the above-mentioned crude benzyl 2-oxo-3-phenyl-1-oxa-3,7-diazaspiro[4.5]decane-7-carboxylate (2.0 g) in ethyl acetate (50 mL) was added 20% palladium hydroxide-carbon (200 mg), and the mixture was stirred at room temperature for 20 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was evaporated under reduced pressure. The residue was washed with diisopropyl ether to give the object product (800 mg, 53%).

Provenance & Evidence