HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-5H-spiro[furo[3,4-b]pyridine-7,4'-piperidine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | 5H-spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride | HCID 67437106 | — |
| Product | 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-5H-spiro[furo[3,4-b]pyridine-7,4'-piperidine] | HCID 68556019 | — |
Reaction Steps
The object product (72 mg, 28%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (150 mg), 5H-spiro[furo[3,4-b]pyridine-7,4′-piperidine] dihydrochloride (86 mg) and potassium carbonate (290 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-e2e1889d09a24c8e93145c5b5c6eabd8 |
| Source note | uspto-grants-2013_11 |