HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]spiro[indene-1,4'-piperidin]-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | spiro[indene-1,4'-piperidin]-3(2H)-one | HCID 18467061 | — |
| Product | 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]spiro[indene-1,4'-piperidin]-3(2H)-one | HCID 68555721 | — |
Reaction Steps
The object product (106 mg, 40%) was obtained in the same manner as in Example 1 and using spiro[indene-1,4′-piperidin]-3(2H)-one (190 mg), 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (150 mg) and potassium carbonate (150 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-4a29d58cf41a49ffa8e20f26885528b9 |
| Source note | uspto-grants-2013_11 |