Potassium Carbonate → HCID 68553101, compound

HRID 2036101Notes

Reaction equation

HRID 2036101 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[S:12][N:11]=[C:10]([CH3:13])[N:9]=2)=[CH:6][CH:7]=1.Cl.[C:15]1([C:21]2[CH2:25][C:24]3([CH2:30][CH2:29][NH:28][CH2:27][CH2:26]3)[O:23][N:22]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(=O)([O-])[O-].[K+].[K+]>>[CH3:13][C:10]1[N:9]=[C:8]([C:5]2[N:4]=[N:3][C:2]([N:28]3[CH2:27][CH2:26][C:24]4([O:23][N:22]=[C:21]([C:15]5[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=5)[CH2:25]4)[CH2:30][CH2:29]3)=[CH:7][CH:6]=2)[S:12][N:11]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 109218293-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazineHCID 68555009HCID 68555009, compound

Product 1

HCID 68553101HCID 68553101, compound

Procedure

The object product (95 mg, 35%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (150 mg), 3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene hydrochloride (200 mg) and potassium carbonate (140 mg).

Sources & evidence

ORD record
ord-2eb443410c3840acbc232a0c9b0f5560
Source dataset
uspto-grants-2013_11
Patent number
US08575167B2

Reaction notes

Loading…