HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 8-[6-(3-Methyl-1,2,4-oxadiazol-5-yl)-3-pyridazinyl]-2-phenyl-2,8-diazaspiro[4.5]decan-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazine | HCID 16732294 | — |
| Reactant | HCID 68557471 | HCID 68557471 | — |
| Product | 8-[6-(3-Methyl-1,2,4-oxadiazol-5-yl)-3-pyridazinyl]-2-phenyl-2,8-diazaspiro[4.5]decan-3-one | HCID 68555266 | — |
Reaction Steps
The object product (142 mg, 64%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazine (111 mg) obtained in Example 43(2), 2-phenyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride (150 mg) and potassium carbonate (155 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-676db6d26da94427b333523f0d206813 |
| Source note | uspto-grants-2013_11 |