HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1'-[6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-3H-spiro[1-benzofuran-2,4'-piperidin]-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazine | HCID 16732294 | — |
| Reactant | 3H-spiro[1-benzofuran-2,4'-piperidin]-3-one hydrochloride | HCID 68557360 | — |
| Product | 1'-[6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-3H-spiro[1-benzofuran-2,4'-piperidin]-3-one | HCID 68555797 | — |
Reaction Steps
The object product (163 mg, 72%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazine (123 mg) obtained in Example 43(2), 3H-spiro[1-benzofuran-2,4′-piperidin]-3-one hydrochloride (150 mg) and potassium carbonate (173 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-c0c5da9aa0cb44cf8888390b0307c013 |
| Source note | uspto-grants-2013_11 |