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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2036346Generated: October 31, 2026

2-(Butyloxy)-8-(methyloxy)-9-{3-[(2S)-tetrahydro-2-furanylamino]propyl}-9H-purin-6-amine → 2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-2-ylmethyl)amino]propyl}-9H-purin-6-amine

https://huagongshe.com/reaction/2036346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Butyloxy)-8-(methyloxy)-9-{3-[(2S)-tetrahydro-2-furanylamino]propyl}-9H-purin-6-amineHCID 67224686—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-2-ylmethyl)amino]propyl}-9H-purin-6-amineHCID 67211368—

Reaction Steps

Prepared similarly to Intermediate 14 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (tetrahydro-2H-pyran)-2-ylmethyl)amine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575181B2
Source datasetuspto-grants-2013_11
ORD IDord-2f51dc03989d4af794e66c8ce148257b
Source noteuspto-grants-2013_11