HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminomethyltetrahydropyran → 2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-4-ylmethyl)amino]propyl}-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| Reactant | 2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2-furanylmethyl)amino]propyl}-9H-purin-6-amine | HCID 67211570 | — |
| Reactant | HCID 178450357 | HCID 178450357 | — |
| Product | 2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-4-ylmethyl)amino]propyl}-9H-purin-6-amine | HCID 67224131 | — |
Reaction Steps
Prepared similarly to Intermediate 15 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (tetrahydro-2H-pyran-4-ylmethyl)amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575181B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-6712c22bfbe34b199f4ea11c91ab594b |
| Source note | uspto-grants-2013_11 |