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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2036350Generated: October 27, 2026

4-Aminomethyltetrahydropyran → 2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-4-ylmethyl)amino]propyl}-9H-purin-6-amine

https://huagongshe.com/reaction/2036350

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminomethyltetrahydropyranHCID 2773210—
Reactant2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2-furanylmethyl)amino]propyl}-9H-purin-6-amineHCID 67211570—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2H-pyran-4-ylmethyl)amino]propyl}-9H-purin-6-amineHCID 67224131—

Reaction Steps

Prepared similarly to Intermediate 15 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (tetrahydro-2H-pyran-4-ylmethyl)amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575181B2
Source datasetuspto-grants-2013_11
ORD IDord-6712c22bfbe34b199f4ea11c91ab594b
Source noteuspto-grants-2013_11