Hydrochloric Acid → HCID 44229352, compound

Participants

Reaction Steps

A mixture of 176 mg of 2-(tetrahydrofuran-3-ylcarbonyl)-N-(tetrahydro-2H-pyran-2-yloxy)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide, 6 ml methanol and 6 ml of an aqueous, 0.1 N hydrochloric acid is stirred overnight at ambient temperature. The reaction mixture is evaporated and the residue is dissolved in a mixture of water and acetonitrile and lyophilized. 140 mg of the title compound are obtained as colorless solid. MH+=291.2

Provenance & Evidence