HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 44229430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 86656616 | HCID 86656616 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 44229430 | HCID 44229430 | 90.1% |
Reaction Steps
To 6.29 g of 2-acetyl-N-(tetrahydro-2H-pyran-2-yloxy)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide are added 57 ml water, 88 ml methanol and 1.4 g DowexWX2-100. The mixture is stirred overnight at ambient temperature and filtered. The filtrate is evaporated and 4.17 g of the title compound as a yellow solid are obtained. MP 177-181° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575193B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-1e046f65ece144edb1dc8dda285746e7 |
| Source note | uspto-grants-2013_11 |