Dimethyl Sulfoxide → 5-bromo-2-(2-ethoxyethyl)-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[Br:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[C:7](=[O:12])[N:6]([CH2:13][CH2:14][OH:15])[CH2:5][CH2:4]2.[CH2:21]([O:22][CH2:23][CH3:24])[CH3:25].[CH3:26][S:27]([CH3:28])=[O:29].[I:18][CH2:19][CH3:20].[K+:17].[OH-:16]>>[Br:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[C:7](=[O:12])[N:6]([CH2:13][CH2:14][O:15][CH2:19][CH3:20])[CH2:5][CH2:4]2Participants
7
Sources & evidence
- ORD record
- ord-8b54b8d2b56749bca0eb5bd591c41898
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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