HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Chloromethyl)cyclopropane → Diethyl [3-(7-cyclopropylmethyl-3-methylxanthin-1-yl)propyl]phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Chloromethyl)cyclopropane | HCID 80013 | — |
| Reactant | Diethyl [3-(3-methyl-xanthin-1-yl)propyl]phosphonate | HCID 22446277 | — |
| Product | Diethyl [3-(7-cyclopropylmethyl-3-methylxanthin-1-yl)propyl]phosphonate | HCID 22446308 | — |
Reaction Steps
The title substance was prepared from 0.015 mol of diethyl [3-(3-methyl-xanthin-1-yl)propyl]phosphonate (Example 42), and 0.017 mol of chloromethylcyclopropane analogously to Example 30 and chromatographed on silica gel (eluent: dichloromethane/methanol 20:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728686 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-465ca427a226420c828105b026a9c1d8 |
| Source note | uspto-grants-1998_03 |