HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(1-Ethyl-propyl)-4-methoxy-pyridine-2-carboxylic acid methyl ester → 6-(1-Ethyl-propyl)-4-methoxy-pyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(1-Ethyl-propyl)-4-methoxy-pyridine-2-carboxylic acid methyl ester | HCID 68630888 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 6-(1-Ethyl-propyl)-4-methoxy-pyridine-2-carboxylic acid | HCID 68630950 | 139.6% |
Reaction Steps
A solution of 6-(1-ethyl-propyl)-4-methoxy-pyridine-2-carboxylic acid methyl ester (450 mg, 1.90 mmol) in 25% aq. HCl is stirred at 65° C. for 18 h. The mixture is concentrated and dried to give the title compound (592 mg) as hydrochloride salt; LC-MS**: tR=0.38 min; [M+1]+=224.32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575200B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-b45eb47f81dd4c3fbb5b8ab653b4bb6c |
| Source note | uspto-grants-2013_11 |