HCID 58109450, compound → HCID 58109599, compound

Participants

Reaction Steps

The title compound was prepared from 3-((R)-3-((S)-1-(4-bromophenyl)ethyl)-6-(4-fluorophenyl)-2-oxo-1,3-oxazinan-6-yl)propanamide following a procedure analogous to that described in Example 612 using ethanol as solvent. LC-MS Method 1 tR=1.83 min, m/z=493, 495 (M+1); 1H NMR (CD3OD) 7.25-7.20 (m, 4H), 7.03 (t, J=8.8 Hz, 2H), 6.81 (d, J=8.2 Hz, 2H), 5.41 (q, J=7.3 Hz, 1H), 3.91 (q, J=7.2 Hz, 2H), 3.10-3.00 (m, 2H), 2.90-2.85 (m, 1H), 2.38-2.34 (m, 1H), 2.22-2.14 (m, 2H), 2.01 (t, J=7.6 Hz, 2H), 1.42 (d, J=7.3 Hz, 3H), 1.10 (t, J=7.2 Hz, 3H).

Provenance & Evidence