Acetic Acid → 1-(3,5-Bis-trifluoromethyl-benzoyl)-4-(3-chloro-phenylamino)-piperidine-4-carbonitrile
Reaction equation
[CH3:32][Si:33]([CH3:34])([CH3:35])[C:36]#[N:37].[CH3:39][C:40](=[O:41])[OH:42].[Cl:24][c:25]1[cH:26][c:27]([NH2:28])[cH:29][cH:30][cH:31]1.[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]1)([F:22])[F:23].[NH3:38]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][C:11]([NH:28][c:27]3[cH:26][c:25]([Cl:24])[cH:31][cH:30][cH:29]3)([C:36]#[N:37])[CH2:12][CH2:13]2)[cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]1)([F:22])[F:23]Participants
6
Sources & evidence
- ORD record
- ord-43ad3906e4c645a0a9a2560c341caa34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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