2-Bromoethanol → HCID 53355056, compound

HRID 2038186Notes

Reaction equation

HRID 2038186 reaction equation
[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:23]C)[N:12]2[CH2:15][CH2:16][CH:17]2[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)=[C:8]([NH2:25])[N:7]=1)[CH2:2][CH2:3][CH3:4].Br[CH2:27][CH2:28][OH:29]>>[NH2:25][C:8]1[N:7]=[C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[N:14]=[C:13]2[C:9]=1[NH:10][C:11](=[O:23])[N:12]2[CH2:15][CH2:16][CH:17]1[CH2:22][CH2:21][N:20]([CH2:27][CH2:28][OH:29])[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 108982-BromoethanolHCID 583062442-(Butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine2×

Product 1

HCID 53355056HCID 53355056, compound

Procedure

Prepared similarly to Example 1 from 2-(butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine (for example, as prepared for Intermediate 30) and 2-bromoethanol (commercially available, for example, from Aldrich).

Sources & evidence

ORD record
ord-a9157e47697d4812ae1a4f25608031b9
Source dataset
uspto-grants-2013_11
Patent number
US08575340B2

Reaction notes

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