2-Methylcyclohexylamine → HCID 69670090, compound

HRID 2038211Notes

Reaction equation

HRID 2038211 reaction equation
CC1CCCCC1N.[CH3:9][O:10][C:11]([CH:13]1[CH2:17][C:16](=[O:18])[N:15]([CH:19]2[CH2:24][CH:23](C)[CH2:22][CH2:21][CH:20]2[CH:26](C)C)[CH2:14]1)=[O:12]>>[CH3:9][O:10][C:11]([CH:13]1[CH2:17][C:16](=[O:18])[N:15]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH:20]2[CH3:26])[CH2:14]1)=[O:12]

Participants

3

Reactant 2

HCID 234322-Methylcyclohexylamine2×HCID 69670044HCID 69670044, compound

Product 1

HCID 69670090HCID 69670090, compound

Procedure

1-(2-Methyl-cyclohexyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester was prepared with 2-methyl-cyclohexylamine in the manner described above for 1-(2-isopropyl-5-methyl-cyclohexyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester of Example I. 2-Methyl-cyclohexylamine (7.4 g, 47.7 mmol) was used to provide 1-(2-methyl-cyclohexyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester (10.7 g, 38.2 mmol).

Sources & evidence

ORD record
ord-24cb882478b74117b8f0745158f37e9f
Source dataset
uspto-grants-2013_11
Patent number
US08575349B2

Reaction notes

Loading…