HRID2038357

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)[C@H]1c2ccc(F)cc2C(F)(F)C[C@]1(O)CCN(C)CCCc1nc2ccccc2[nH]1

HCID68750604

未命名化合物

结构：[2H]C1([2H])c2cc(F)ccc2C(C(C)C)C(OC(=O)COC)C1([2H])[2H]

HCID86665242

3,3,4,4-Tetradeutero-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate

C16H21FO3

PRODUCTS

生成物

结构：COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CC(F)(F)c2cc(F)ccc2[C@@H]1C(C)C

HCID68750530

未命名化合物

PROCEDURE

实验过程

Compound 104 is prepared from 35d in a manner analogous to that of Example 4 for compound 500.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-aef9cabb61b4418f887308d61935248d
来源数据集: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08575361B2
来源说明: uspto-grants-2013_11

反应 SMILES

[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:10][CH2:11][CH2:12][N:13]([CH3:33])[CH2:14][CH2:15][C@@:16]1([OH:32])[CH2:25][C:24]([F:27])([F:26])[C:23]2[C:18](=[CH:19][CH:20]=[C:21]([F:28])[CH:22]=2)[C@@H:17]1[CH:29]([CH3:31])[CH3:30].[CH3:34][O:35][CH2:36][C:37](OC1C([2H])([2H])C([2H])([2H])C2C(=CC=C(F)C=2)C1C(C)C)=[O:38]>>[CH3:34][O:35][CH2:36][C:37]([O:32][C@:16]1([CH2:15][CH2:14][N:13]([CH2:12][CH2:11][CH2:10][C:2]2[NH:3][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[N:1]=2)[CH3:33])[CH2:25][C:24]([F:27])([F:26])[C:23]2[C:18](=[CH:19][CH:20]=[C:21]([F:28])[CH:22]=2)[C@@H:17]1[CH:29]([CH3:31])[CH3:30])=[O:38]