(1S,2R)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-4,4,6-trifluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-ol → (1S,2R)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-4,4,6-trifluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate

Participants

Role	Name	HCID	Charge
Reactant	(1S,2R)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-4,4,6-trifluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-ol	HCID 68750604	—
Reactant	3,3,4,4-Tetradeutero-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate	HCID 86665242	—
Product	(1S,2R)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-4,4,6-trifluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate	HCID 68750530	—

Compound 104 is prepared from 35d in a manner analogous to that of Example 4 for compound 500.