HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-{[5-(3-Chloro-4-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one → 1-{[4-(3-Chloro-5-fluorophenyl)-5-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-{[5-(3-Chloro-4-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one | HCID 50942915 | — |
| Reactant | 5-(3-Chloro-4-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-carboxylic acid | HCID 70801737 | — |
| Product | 1-{[4-(3-Chloro-5-fluorophenyl)-5-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one | HCID 50942916 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 4 starting with the compound from Example 11A. 4.5 mg (19% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575357B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a25d73920c5a483ba99ff3e45f0b18e6 |
| Source note | uspto-grants-2013_11 |