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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2038748Generated: November 1, 2026

Hydrochloric Acid → HCID 68378932, compound

https://huagongshe.com/reaction/2038748

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67508138HCID 67508138—
SolventDichloromethaneHCID 6344—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68378932HCID 68378932—

Reaction Steps

{1-[5-(2-Methyl-imidazo[1,2-a]pyridin-6-yl)-pyridin-2-yl]-cyclopropyl}-carbamic acid tert-butyl ester (21 mg, 0.06 mmol) was dissolved in 0.5 mL of CH2Cl2 and 1 mL of 4M HCl in dioxane was added. The resulting suspension was stirred for 1 h. The mixture was concentrated to yield crude 1-[5-(2-methyl-imidazo[1,2-a]pyridin-6-yl)-pyridin-2-yl]-cyclopropylamine dihydrochloride. The material was used in subsequent reactions without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575360B2
Source datasetuspto-grants-2013_11
ORD IDord-76b627fd0a3c4ed9a29f5ddb04f935c3
Source noteuspto-grants-2013_11